Endocrine Abstracts

Diabetes insipidus is mainly associated with dehydration as a complication, hyponatremia being very rare. We report the case of a 75 years old female, from Switzerland, who presented with nausea and vomit, diarrhea, asthenia and general sickness at the emergency room, where blood tests revealed hyperglycemia of 320 mg/dl and hyponatremia of 115 mmol/l, the patient knowing to have diabetes insipidus and diabetes mellitus type II, with insulin and desmopressin. Following emergen...

Introduction: Parathyroid carcinoma and atypical parathyroid adenoma are among rarely encountered causes of primary hyperparathyroidism. Patients with parathyroid carcinoma often differ from those with atypical parathyroid adenoma or parathyromatosis at the time of presentation because patients with parathyroid carcinoma have more profound hypercalcemia as well as invasive tumors. However, at times, it is difficult to distinguish between these conditions both clinically and by...

Introduction: Pituitary apoplexy is a rare and potentially life-threatening disorder defined by hemorrhage or infarction of the pituitary gland. Occasionally, it may be the first manifestation of an underlying adenoma.Case report: We present a case of a 70-year-old male, who was admitted in our clinic for an incidentally discovered pituitary macroadenoma accompanied by severe left hemicrania, otalgia and left eyelid ptosis.Medical ...

The aim of our study was to investigate de relationship between anthropometric and body composition parameters and thyroid function (measured with TSH and free T4), as well as thyroid volume, in patients with obesity.Methods: This is a cross-sectional study including patients with obesity consecutively referred to our tertiary endocrine center for diverse pathologies. TSH and free T4 was measured in all patients and thyroid ultrasound was performed by an...

Introduction: We report a case of papillary thyroid carcinoma recurrence. According to most of the guidelines, patients with PTC have recurrences in the first 5 years after diagnosis and the most rigorous follow-up is indicated in this time; however metastasis are reported beyond this period and are associated mostly with lack of adherence to follow-up.Case report: A 76-year-old female was admitted in our department for the evaluation of a 5 cm laterocer...

Osteopetrosis and O.I. are both bone metabolic disorders with opposite features in terms of the metabolic turnover: while osteopetrozis has a low turnover and increased BMD due to the failure of osteoclasts to resorb bone, O.I. is well known as a high turnover disease with low BMD caused bt mutations in the COL1A1 and col COL1A2 genes that encode type 1 procollagen; yet, both condition, in spite of different mechanism, end up with increased ftracure prevalence. We report the c...

Background: Primary hyperparathyroidism is usually a long evolving disease before the diagnosis, thus patients who are not diagnosed by routine screening tests may have a lot of complications affecting the bone, kidney, bone marrow.Aim: Pointing out the possibility of fast recovery not only for bone mass.Material: We present a case of primary hyperparathyroidism, a female patient 66 years old, sent to emergency room, dehydrated, as...

Introduction: We report a case of severe osteoporosis with incident fragility fractures during antiresorbtive therapy in the presence of amiodarone induced hypothyroidism.Case report: A 76 year old female was admitted in our department for the evaluation of antiresorbtive therapy in the context of a recent rib fracture after coughing. Severe osteoporosis (lumbar T-score: −2.8DS, femoral neck T-score: −2.9DS with multiple fra...

Background: Previous studies suggested that treatment with somatropinum in children with GH deficiency (GHD) may alter lipid profile and pituitary–thyroid axis function. However, results are divergent and data regarding a possible association between changes of thyroid function and of circulating lipids are scarce. The aim of this study was to report the changes of the lipid profile in children with GHD treated with somatropinum and the relationship between thyroid functi...

Introduction: Multiple factors have been incriminated in growth retardation in patients with chronic kidney disease (CKD), such as metabolic acidosis, anemia, vitamin D deficiency with secondary hyperparathyroidism, under-nutrition, renal bone disease. The disease compromises vertical growth with up to one-third children having severe growth delay (below the third percentile for height). Optimal care and nutritional therapy alone, can’t help the children with CKD reach t...